Medical | Dynamics of Cancer: Incidence, Inheritance, and Evolution (Princeton Series in Evolutionary Biology)

Steven A. Frank , "Dynamics of Cancer: Incidence, Inheritance, and Evolution (Princeton Series in Evolutionary Biology)"
Publisher: Princeton University Press | ISBN: 0691133662 | 400 Pages | PDF | 2.8 Mb

The onset of cancer presents one of the most fundamental problems in modern biology. In Dynamics of Cancer, Steven Frank produces the first comprehensive analysis of how particular genetic and environmental causes influence the age of onset.

The book provides a unique conceptual and historical framework for understanding the causes of cancer and other diseases that increase with age. Using a novel quantitative framework of reliability and multistage breakdown, Frank unifies molecular, demographic, and evolutionary levels of analysis. He interprets a wide variety of observations on the age of cancer onset, the genetic and environmental causes of disease, and the organization of tissues with regard to stem cell biology and somatic mutation. Frank uses new quantitative methods to tackle some of the classic problems in cancer biology and aging: how the rate of increase in the incidence of lung cancer declines after individuals quit smoking, the distinction between the dosage of a chemical carcinogen and the time of exposure, and the role of inherited genetic variation in familial patterns of cancer.

This is the only book that presents a full analysis of the age of cancer onset. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For cancer biologists, population geneticists, evolutionary biologists, and demographers interested in aging, this book provides new insight into disease progression, the inheritance of predisposition to disease, and the evolutionary processes that have shaped organismal design.

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Thing Knowledge: A Philosophy of Scientific Instruments

Thing Knowledge: A Philosophy of Scientific Instruments
University of California Press | ISBN 0520232496 | 2004 Edition | PDF | 171 Pages | 3.2 MB

Western philosophers have traditionally concentrated on theory as the means for expressing knowledge about a variety of phenomena. This absorbing book challenges this fundamental notion by showing how objects themselves, specifically scientific instruments, can express knowledge. As he considers numerous intriguing examples, Davis Baird gives us the tools to "read" the material products of science and technology and to understand their place in culture. Making a provocative and original challenge to our conception of knowledge itself, Thing Knowledge demands that we take a new look at theories of science and technology, knowledge, progress, and change. Baird considers a wide range of instruments, including Faraday's first electric motor, eighteenth-century mechanical models of the solar system, the cyclotron, various instruments developed by analytical chemists between 1930 and 1960, spectrometers, and more.

"From the air pump to the dynamo to the cyclotron, machines have played key roles in the development of scientific knowledge. Here, for the first time, Davis Baird looks at those machines as actual forms of scientific knowledge. Baird moves adeptly from historical case study to philosophical explanation in this convincing study of the material culture of science."--Ann Johnson, Department of History, Fordham University

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Macroeconomic Essentials

Macroeconomic Essentials - Understanding Economics in the News
The MIT Press | ISBN 0262611503 | 2000 edition | CHTM File | 432 pages | 740 KB


The book provides a guide to what the author calls the "really important" ideas of macroeconomics, with a strong connection to the real world. Thus many instructors will find the book suitable for use in courses enrolling business students. The method of presentation allows room for topics that are crucial for the interpretation of news commentary, but given inadequate coverage in traditional macroeconomics texts. Examples include the many roles of nominal versus real interest rates, and international phenomena such as purchasing power parity.

Despite its nontechnical presentation, the material in the book is quite challenging for students; to answer questions based on the news clips, students must truly understand the economic concepts and apply problem-solving skills rather than rote learning. This text, unlike other economic texts, provides the student with a practical yet sophisticated grasp of the macroeconomic principles necessary to interpret media commentary. The second edition has been revised and updated throughout.

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Get Clients Now!: A 28-day Marketing Program for Professionals, Consultants, And Coaches

C. J. Hayden, "Get Clients Now!: A 28-day Marketing Program for Professionals, Consultants, And Coaches"
AMACOM/American Management Association | ISBN-10: 0814473741 | 239 pages | PDF | 3,9 Mb

Foreword by Jay Conrad Levinson, author of the "Guerilla Marketing" series

Get Clients Now empowers readers with its 28-day plan for energizing their marketing efforts and dramatically increasing their client base. With over 100 tactics, tools, and foolproof recipes customizable for any professional service business, this new edition is powered up with road-tested strategies for relationship-based marketing in the Internet age, plus proven techniques for overcoming the fear, resistance, and procrastination that block effective action.

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